Researchers on Thursday reported the latest in a surprising string of experiments in the quest to save human lives with organs from genetically modified pigs.

WASHINGTON (AP) — President Joe Biden ends his first year in the White House with a clear majority of Americans for the first time disapproving of his handling of the presidency in the face of an …

PHILADELPHIA (AP) — The pilot of a medical helicopter that crash-landed without loss of life next to a church in a residential area of suburban Philadelphia last week expressed gratitude to his crew and first responders as he was released from a hospital Sunday.

BIRMINGHAM, Ala. (AP) — A new effort to preserve historic Black churches in the United States has received a $20 million donation that will go to help congregations including one that was slammed …

WASHINGTON (AP) — The Supreme Court said Friday it will hear the case of a former Seattle-area football coach who was removed from his job because he refused to stop praying on the field.

SACRAMENTO, Calif. (AP) — Sirhan Sirhan, who assassinated presidential candidate Robert F. Kennedy in 1968, was denied parole Thursday by California’s governor, who said the killer remains a threat to the public and hasn’t taken responsibility for a crime that altered American history.

WASHINGTON (AP) — The Supreme Court has stopped a major push by the Biden administration to boost the nation's COVID-19 vaccination rate, a requirement that employees at large businesses get a vaccine or test regularly and wear a mask on the job.

In a medical first, doctors transplanted a pig heart into a patient in a last-ditch effort to save his life and a Maryland hospital said Monday that he's doing well three days after the highly experimental surgery.

WASHINGTON (AP) — A snowy owl apparently touring iconic buildings of the nation's capital is captivating birdwatchers who manage to get a glimpse of the rare, resplendent visitor from the Arctic.

NEW YORK (AP) — Doctors worked Monday to save the lives of multiple people gravely injured when smoke from a fire knocked them out or trapped them in their apartments in a New York City high-rise building. Nineteen people, including nine children, died in the blaze.

NEW YORK (AP) — At least 19 people, including nine children, died in a fire Sunday at a Bronx apartment building in New York City's deadliest blaze in more than three decades.

NEW YORK (AP) — Five Americans died of rabies last year — the largest number in a decade — and health officials said Thursday that some of the people didn't realize they had been infected or refused life-saving shots.

An unidentified person paid a ransom that freed three missionaries kidnapped by a gang in Haiti under an agreement that was supposed to have led to the release of all 15 remaining captives early last month, workers for their Ohio-based organization have confirmed.

PHILADELPHIA (AP) — Fire tore through a duplex home early Wednesday in Philadelphia, killing 12 people, including eight children, fire officials said.

RUTHER GLEN, Va. (AP) — Hundreds of motorists were stranded all night in snow and freezing temperatures along a 50-mile stretch of Interstate 95 after a crash involving six tractor-trailers in Virginia, where authorities were struggling Tuesday to reach them.

WASHINGTON (AP) — A winter storm packing heavy snow blew into the nation's capital on Monday, closing government offices and schools and grounding the president's helicopter.

RICHMOND, Va. (AP) — In the tiny town of Lawrenceville, Virginia, a van owned by Poplar Mount Baptist Church was knocked out of commission for weeks after thieves cut the catalytic converter out of its exhaust system.

SUPERIOR, Colo. (AP) — A Colorado official says nearly 1,000 homes were destroyed, hundreds more were damaged, and three people are missing after a wildfire charred numerous neighborhoods in a suburban area at the base of the Rocky Mountains.

LOS ANGELES (AP) — Betty White, whose saucy, up-for-anything charm made her a television mainstay for more than 60 years, whether as a man-crazy TV hostess on “The Mary Tyler Moore Show” or the loopy housemate on “The Golden Girls,” has died.

DENVER (AP) — Tens of thousands of Coloradans driven from their neighborhoods by wind-whipped wildfires anxiously waited to learn what was left standing of their lives Friday after the flames burned an estimated 580 homes, a hotel and a shopping center

PORTLAND, Maine (AP) — The U.S Postal Service pulled out all the stops to avoid a repeat of the 2020 holiday shipping disaster, and it worked. The Postal Service and several other private …

They both carved out sterling reputations as military and political leaders over years of public service. But both also saw their legacies tarnished by their actions in the long, bloody war in Iraq. Former Secretary of State Colin Powell and former Defense Secretary Donald Rumsfeld are among the many noteworthy people who died in 2021.

NEW YORK (AP) — U.S. health officials on Monday cut isolation restrictions for Americans who catch the coronavirus from 10 to five days, and similarly shortened the time that close contacts need to quarantine.

SAN FRANCISCO (AP) — Blowing snow in mountains of Northern California and Nevada closed key highways over the weekend, while an arctic blast brought frigid temperatures to the Pacific Northwest, and unusually warm weather settled over parts of Texas and the Southeast.

SEATTLE (AP) — Emergency warming shelters were opened throughout western Washington and Oregon as temperatures plunged into the teens and forecasters said an arctic blast would last for several days.